It is a chronic genetic disease in the blood characterized by a change in the red blood cells shape from the natural round shape to the sickle or crescent shape. Change in the form of cells leads to a change in their properties, as their elasticity and ease lose their flow in the blood vessels and the bone marrow, which leads to chronic decay in the blood with clogged episodes of the vessels and the bone marrow that leads to severe pain.
Severe pain episodes: It is considered one of the main symptoms of sickle cell anemia. The pain differs in its intensity and may last for a few hours or days. Adults may experience chronic pain as a result of damage to the bones and joints.
Hemolysis: a severe decrease in the usual rate of hemoglobin as a result of hemolysis (red blood cell destruction when the immune system attacks these cells), which may coincide with severe pain. Common symptoms are general fatigue, inability to perform the daily effort, and redness of urine color.
Repeated infections: sickle cell anemia causes spleen damage and infection's ability, especially in children.