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Stimulation/provocation Test Of Puberty Hormones With Subcutaneous Triptorelint

  • The purpose of this test is to determine if there is excessive or deficient secretion of puberty hormones from the pituitary gland, especially luteinizing hormone which is the most important hormone for puberty in children. This analysis is performed in cases of precocious (early) and delayed puberty in adolescents.
  • The stimulation test is a diagnostic procedure, not a therapeutic one.
  • The purpose of the test is to assess the pituitary gland's reserve of puberty-related hormones.
  • Puberty hormones are secreted by the pituitary gland in a pulsatile like pattern, which means their peak levels cannot be accurately measured through random blood tests.
  • So stimulation done for provoking the secretion of stored puberty hormones in the patient using subcutaneous triptorelin, which triggers the release of these stored hormones from the pituitary gland (this medication is considered very safe, and its effectiveness does not exceed three hours).
  • After administering the medication, blood samples are taken every 15 minutes in first hour & last sample after 1 hour, 4-6 samples over 2 hours.
  • An experienced nurse will monitor the patient’s vital signs every 30 minutes, under the supervision of the attending physician.
  • Parental consent for the stimulation must be obtained.
  • After obtaining the necessary approvals, parents must visit the nursing department on the second floor to verify the approvals and register the child’s name in the hormone stimulation-scheduling log. The head nurse must be notified to ensure the preparation of the stimulation room and the assignment of an experienced nurse.
  • Nurses from pediatric department will contact the parents to confirm the date & time of the scheduled test.
  • A copy of these instructions will be given to the parents to avoid any confusion regarding the stimulation test and its preparation.
  • If there are any questions or concerns, please consult the attending physician.

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